DRUGS FOR BREAST CANCER TREATMENT AND PREVENTION
TAMOXIFEN
Tamoxifen is a drug used to treat breast cancer. It was approved by the United States food and drug administration (FDA) in 1998 for the treatment of breast cancer. For years tamoxifen has being used to treat women who are diagnosed with breast cancer, However, tamoxifen carries with it life threaten side effects, including risk of uterine cancer and blood clots. As reported by the United States national cancer institute (NCI) on April 6, 1998.
Tamoxifen is a drug that can prevent breast cancer from reoccurring in women who have suffered from breast cancer in the past. tamoxifen has also be shown to reduced the risk of breast cancer in women caring a mutation in the BRCA2 gene which produces tumors that require estrogen to grow (estrogen is a hormone found in women)
Although tamoxifen does not reduce risk of breast cancer in women caring the BRCA1 gene which producing tumors that is not affected by estrogen.
Tamoxifen may also prevent new cancer from forming in the other breast of the patient. Though tamoxifen is valuable to some patients, doctors are advised by FDA to weigh the benefits and the risk of tamoxifen before the patient can use the drug.
More to come.
RALOXIFEN
Raloxifen is another breast cancer preventive drug; it’s very effective because on like tamoxifen, raloxifen reduces the risk of breast cancer. Interestingly raloxifen is not only effective in the treatment of breast cancer but also in other diseases such as osteoporosis (osteoporosis is the a bone degenerative condition)
Both tamoxifen and ramoxifen belong to new class of drug know as selective estrogen receptors modulators (SERMs). This drug imitates the effects of estrogen. Estrogen which has being linked to breast cancer growth.
Ultimately the use of these drugs depends on the type of breast cancer and the current staging period.
FACTORS THAT COULD INFLUENCE THE DEVELOPMENT OF BREAST CANCER
1) Advancing age
2) A family history of the diseases
3) A personal history of noncancerous lumps.
4) Giving birth for the first time after 30 years.
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